Description

n-Fmoc-R-2-Amino-Nonanoic Acid is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for the solid-phase synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing therapeutic peptides and investigating protein-protein interactions.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the sequential assembly of custom peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and development of novel peptide-based therapeutics and bioactive compounds.
• Peptidomimetic Design: Incorporates non-natural side chains to enhance metabolic stability, bioavailability, and binding affinity of peptide analogs.
• Bioconjugation and Probe Synthesis: Serves as a precursor for labeling peptides with fluorescent tags, biotin, or other functional groups.
• Academic Research: Employed in biochemical and biophysical studies to understand protein structure-function relationships.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse libraries of peptide-like molecules for high-throughput screening.

Basic Information

Product Name	n-Fmoc-R-2-Amino-Nonanoic Acid
CAS No.	1262886-66-7
Molecular Formula	C₂₄H₂₉NO₄
Molecular Weight	395.49 g/mol
Synonyms	Fmoc-2-Aminononanoic Acid; Fmoc-D-2-Aminononanoic Acid; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)nonanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (extended chain analog); Fmoc-D-Nle-OH (extended); Fmoc-D-2-amino-nonanoate; N-α-Fmoc-D-2-aminononanoic acid
EINECS	Contact for details

Quality Control

Our n-Fmoc-R-2-Amino-Nonanoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (R-isomer)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.