Description

2-Formyl-6-(2-Trifluoromethylphenyl)Phenol is a specialized aromatic aldehyde building block featuring a phenolic hydroxyl group and a trifluoromethyl substituent. This compound is valued for its unique molecular architecture, which combines the electron-withdrawing properties of the trifluoromethyl group with the reactivity of both aldehyde and phenol functionalities. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates. The presence of fluorine atoms can significantly enhance the metabolic stability, bioavailability, and binding affinity of target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic structure.
• Chemical Biology Probes: Useful for designing fluorescent tags or molecular probes to study enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-Formyl-6-(2-Trifluoromethylphenyl)Phenol
CAS No.	1261930-44-2
Molecular Formula	C14H9F3O2
Molecular Weight	266.22 g/mol
Synonyms	6-(2-(Trifluoromethyl)phenyl)-2-hydroxybenzaldehyde; 2-Hydroxy-6-[2-(trifluoromethyl)phenyl]benzaldehyde; 2-Hydroxy-6-(α,α,α-trifluoro-o-tolyl)benzaldehyde; 2-Formyl-6-(2-trifluoromethylphenyl)phenol; 2-(2-Trifluoromethylphenyl)-6-hydroxybenzaldehyde; o-(2-Hydroxy-6-formylphenyl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Formyl-6-(2-Trifluoromethylphenyl)Phenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.