Description

2-Chloro-4-(4-Fluoro-3-Methoxyphenyl)Phenol is a high-purity, multi-functional phenolic intermediate with a distinct halogenated and methoxylated aromatic structure. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering precise reactivity for complex molecular architectures. Industries requiring fine chemical synthesis, particularly in pharmaceutical R&D, agrochemical development, and specialty polymer production, will find this material essential for their processes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a precursor for advanced herbicides and fungicides, leveraging its halogenated phenol core for enhanced biological activity.
• Liquid Crystal & OLED Material Development: Used in the synthesis of specialized aromatic cores for electronic display and lighting applications due to its stable, planar structure.
• Polymer Modification: Acts as a functional monomer or additive to impart specific properties like flame retardancy or UV stability to engineering plastics and resins.
• Organic Synthesis & Chemical Research: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and for introducing complex phenolic motifs in academic and industrial laboratories.

Basic Information

Product Name	2-Chloro-4-(4-Fluoro-3-Methoxyphenyl)Phenol
CAS No.	1261920-40-4
Molecular Formula	C13H10ClFO2
Molecular Weight	252.67 g/mol
Synonyms	2-Chloro-4-(4-fluoro-3-methoxyphenyl)phenol; 4-(4-Fluoro-3-methoxyphenyl)-2-chlorophenol; 2-Chloro-4'-(4-fluoro-3-methoxy)biphenyl-4-ol; 2-Chloro-4-(4-fluoro-3-methoxy-1,1'-biphenyl-4-yl)phenol; Phenol, 2-chloro-4-(4-fluoro-3-methoxyphenyl)-; Biphenyl-4-ol, 2-chloro-4'-(4-fluoro-3-methoxy)-; [1261920-40-4]
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Fluoro-3-Methoxyphenyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.