Description

2-Bromo-5-(Difluoromethoxy)Aniline is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines bromine and difluoromethoxy substituents to impart specific electronic and steric properties for creating novel active molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Material Science Research: Employed as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic systems for asymmetric synthesis and cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-5-(Difluoromethoxy)Aniline
CAS No.	1261875-41-5
Molecular Formula	C7H6BrF2NO
Molecular Weight	238.03 g/mol
Synonyms	2-Bromo-5-(difluoromethoxy)benzenamine; 1-Amino-2-bromo-5-(difluoromethoxy)benzene; Benzenamine, 2-bromo-5-(difluoromethoxy)-; 5-(Difluoromethoxy)-2-bromoaniline; 2-Bromo-5-difluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Difluoromethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.