Description

3-(Hydroxymethyl)-4-(Trifluoromethoxy)Phenol is a versatile trifluoromethoxy-substituted phenolic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a hydroxymethyl and a phenol group, makes it a critical intermediate for constructing complex molecules with enhanced properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical resistance.
• Organic Electronic Materials: Investigated as a building block for electron-transport materials or hole-blocking layers in OLEDs and other electronic devices.
• Chemical Research: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	3-(Hydroxymethyl)-4-(Trifluoromethoxy)Phenol
CAS No.	1261863-34-6
Molecular Formula	C8H7F3O3
Molecular Weight	208.14 g/mol
Synonyms	4-(Trifluoromethoxy)-3-(hydroxymethyl)phenol; 3-Hydroxymethyl-4-trifluoromethoxyphenol; 1-Hydroxy-2-(hydroxymethyl)-5-(trifluoromethoxy)benzene; 2-(Hydroxymethyl)-5-(trifluoromethoxy)phenol; Phenol, 3-(hydroxymethyl)-4-(trifluoromethoxy)-; CAS 1261863-34-6
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)-4-(Trifluoromethoxy)Phenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and manufacturing. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.