Description

2-Trifluoromethoxy-4-Nitroaniline is a specialized aromatic amine derivative featuring both nitro and trifluoromethoxy functional groups, making it a valuable intermediate in advanced organic synthesis. This compound is particularly significant for its role in the development of complex molecules, where its unique electronic and steric properties are leveraged. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Dye and Pigment Precursor: Serves as an intermediate in the manufacture of specialized azo dyes and pigments, contributing to color fastness and unique spectral properties.
• Liquid Crystal and Electronic Material Research: Employed in the development of advanced organic electronic materials and liquid crystal displays (LCDs) due to its polarizable aromatic structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex biaryl amines.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Detail
Product Name	2-Trifluoromethoxy-4-Nitroaniline
CAS No.	1261753-88-1
Molecular Formula	C7H5F3N2O3
Molecular Weight	222.12 g/mol
Synonyms	4-Nitro-2-(trifluoromethoxy)aniline; 2-Amino-5-nitro-1-(trifluoromethoxy)benzene; 1-Amino-2-trifluoromethoxy-4-nitrobenzene; 4-Nitro-2-trifluoromethoxyaniline; 2-Trifluoromethoxy-4-nitrobenzenamine; 2-(Trifluoromethoxy)-4-nitroaniline; AN-698/34200036; BBL027209
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethoxy-4-Nitroaniline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.