Description

[5-Methoxy-2-(Trifluoromethyl)Phenyl]Methanol is a high-value fluorinated aromatic alcohol building block. This compound matters for its unique trifluoromethyl and methoxy substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or chain modifier to introduce fluorine atoms into specialty polymers, improving chemical resistance and surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions, esterifications, and other transformations to create complex molecular architectures.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	[5-Methoxy-2-(Trifluoromethyl)Phenyl]Methanol
CAS No.	1261682-03-4
Molecular Formula	C9H9F3O2
Molecular Weight	206.16 g/mol
Synonyms	5-Methoxy-2-(trifluoromethyl)benzyl alcohol; (5-Methoxy-2-(trifluoromethyl)phenyl)methanol; 2-(Trifluoromethyl)-5-methoxybenzenemethanol; α-(Trifluoromethyl)-5-methoxy-o-tolyl alcohol; 1-[5-Methoxy-2-(trifluoromethyl)phenyl]methanol; 5-Methoxy-α,α,α-trifluoro-o-toluyl alcohol
EINECS	Contact for details

Quality Control

Our [5-Methoxy-2-(Trifluoromethyl)Phenyl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.