Description

3-Methoxy-4-(Trifluoromethoxy)Phenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique combination of the methoxy and trifluoromethoxy substituents, which impart desirable electronic and steric properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group improves bioavailability and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in the production of high-performance liquid crystal displays (LCDs).
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, enhancing thermal stability and chemical resistance.
• Organic Electronic Materials: Utilized in the research and development of organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial R&D labs.

Basic Information

Product Name	3-Methoxy-4-(Trifluoromethoxy)Phenol
CAS No.	1261571-61-2
Molecular Formula	C8H7F3O3
Molecular Weight	208.14 g/mol
Synonyms	4-Hydroxy-2-methoxy-1-(trifluoromethoxy)benzene; 1-Hydroxy-2-methoxy-4-(trifluoromethoxy)benzene; 2-Methoxy-4-(trifluoromethoxy)phenol; 3-Methoxy-4-(trifluoromethoxy)benzenol; Phenol, 3-methoxy-4-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-(Trifluoromethoxy)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.