Description

2-Pyrrolidin-1-Yl-5,6,7,8-Tetrahydro-Pyrido[4,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate with the CAS number 1260982-43-1. This compound is a critical building block in modern medicinal chemistry, valued for its complex heterocyclic structure which serves as a key scaffold in drug discovery and development. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Drug Discovery & Research: Serves as a versatile scaffold in medicinal chemistry for creating compound libraries and probing structure-activity relationships (SAR).
• Oncology Research: Used in the development of potential anti-cancer agents due to its pyrido[4,3-d]pyrimidine core, which is common in many therapeutic candidates.
• CNS-Active Compound Synthesis: Employed in research programs targeting neurological disorders.
• Chemical Biology Probes: Utilized to develop tools for studying biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-Pyrrolidin-1-Yl-5,6,7,8-Tetrahydro-Pyrido[4,3-D]Pyrimidine
CAS No.	1260982-43-1
Molecular Formula	C14H20N4
Molecular Weight	244.34 g/mol
Synonyms	5,6,7,8-Tetrahydro-2-(1-pyrrolidinyl)pyrido[4,3-d]pyrimidine; 2-(Pyrrolidin-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; UNII-8J4Q2K8Q6F; Pyrrolidine, 1-(5,6,7,8-tetrahydro-4-pyrido[4,3-d]pyrimidinyl)-; 8J4Q2K8Q6F; 2-(1-Pyrrolidinyl)-5,6,7,8-tetrahydro-4-pyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidin-1-Yl-5,6,7,8-Tetrahydro-Pyrido[4,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.