Description

2,2,2-Trifluoro-1-(7-Nitro-3-Indolyl)Ethanone is a specialized fluorinated indole derivative that serves as a high-value synthetic intermediate. Its unique structure, featuring both a trifluoroacetyl group and a nitro-substituted indole core, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in medicinal chemistry, chemical biology, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for developing protease inhibitors, kinase inhibitors, and other targeted therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators with enhanced activity and selectivity.
• Chemical Biology Probe: Serves as a core scaffold for creating fluorescent tags, photoaffinity labels, and activity-based probes to study biological processes.
• Material Science: Employed in the synthesis of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing properties.
• Academic & Contract Research: Essential for organic synthesis research in universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry and fluorination methodologies.

Basic Information

Product Name	2,2,2-Trifluoro-1-(7-Nitro-3-Indolyl)Ethanone
CAS No.	1260890-74-1
Molecular Formula	C₁₀H₅F₃N₂O₃
Molecular Weight	258.16 g/mol
Synonyms	2,2,2-Trifluoro-1-(7-nitro-1H-indol-3-yl)ethanone; 1-(7-Nitro-1H-indol-3-yl)-2,2,2-trifluoroethanone; 7-Nitro-3-trifluoroacetylindole; 3-Trifluoroacetyl-7-nitroindole; 2,2,2-Trifluoro-1-(7-nitroindol-3-yl)ethan-1-one; TFAN; 7-Nitroindole-3-carboxylic acid trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Trifluoro-1-(7-Nitro-3-Indolyl)Ethanone is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR, IR, and MS), and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.