Description

1-Methyl-3-(5-Methylisoxazol-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Kinase Inhibitor Research: Used in the research and development of potent and selective kinase inhibitors, leveraging its pyrazolopyrimidine core scaffold.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop novel drug candidates.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study specific enzyme pathways and cellular mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	1-Methyl-3-(5-Methylisoxazol-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ol
CAS No.	1260876-64-9
Molecular Formula	C12H11N5O2
Molecular Weight	257.25 g/mol
Synonyms	1-Methyl-3-(5-methyl-3-isoxazolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol; 4-Hydroxy-1-methyl-3-(5-methylisoxazol-3-yl)-1H-pyrazolo[3,4-d]pyrimidine; 1-Methyl-3-(5-methyl-1,2-oxazol-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol; UNII-5J6Q8VW2U8; 5J6Q8VW2U8; SCHEMBL218064; AKOS025147324; A-205804.0
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-(5-Methylisoxazol-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.