Description

2-Fluoro-6-Iodo-3-Methylbenzaldehyde is a high-purity, multi-functional halogenated benzaldehyde derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated and iodinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the unique electronic properties of fluorine and iodine substituents.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing functionalized organic molecules for organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Serves as a starting material for creating fluorescent tags or molecular probes for imaging and diagnostic applications.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.

Basic Information

Product Name	2-Fluoro-6-Iodo-3-Methylbenzaldehyde
CAS No.	1260839-45-9
Molecular Formula	C8H6FIO
Molecular Weight	264.04 g/mol
Synonyms	3-Methyl-2-fluoro-6-iodobenzaldehyde; 2-Fluoro-6-iodo-3-methylbenzaldehyde; 6-Iodo-2-fluoro-3-methylbenzaldehyde; Benzaldehyde, 2-fluoro-6-iodo-3-methyl-; (2-Fluoro-6-iodo-3-methylphenyl)methanal
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Iodo-3-Methylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.