Description

3-Bromo-2,4,5-Trifluorobenzyl Alcohol 95+% is a high-purity fluorinated benzyl alcohol derivative, serving as a critical multifunctional building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine substituents, which enable precise regioselective coupling reactions and modulate the electronic properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport materials in organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Functional Group Transformation: The benzyl alcohol group can be readily oxidized to the corresponding aldehyde or esterified, providing a handle for further molecular diversification.
• Material Science Research: Employed in the development of novel fluorinated polymers and specialty chemicals with unique surface properties and chemical resistance.

Basic Information

Product Name	3-Bromo-2,4,5-Trifluorobenzyl Alcohol 95+%
CAS No.	1260825-79-3
Molecular Formula	C7H3BrF3O
Molecular Weight	237.00 g/mol
Synonyms	(3-Bromo-2,4,5-trifluorophenyl)methanol; 2,4,5-Trifluoro-3-bromobenzyl Alcohol; 1-(Bromomethyl)-2,4,5-trifluoro-3-bromobenzene (incorrect but common misnomer); α-Hydroxymethyl-3-bromo-2,4,5-trifluorotoluene; Benzenemethanol, 3-bromo-2,4,5-trifluoro-; 3-Bromo-2,4,5-trifluorobenzylalcohol; 3-Br-2,4,5-F3-BnOH
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,4,5-Trifluorobenzyl Alcohol is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.