Description

5-Chloro-2-Iodo-4-Methylpyrimidine is a high-purity halogenated pyrimidine building block of significant importance in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex heterocyclic systems. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a starting material for creating functionalized organic molecules used in electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Nucleoside Analog Synthesis: Employed in the research of modified nucleosides and nucleotides.
• Chemical Biology Probes: Used to create tagged or labeled molecules for studying biological processes and target engagement.

Basic Information

Product Name	5-Chloro-2-Iodo-4-Methylpyrimidine
CAS No.	1260810-52-3
Molecular Formula	C5H4ClIN2
Molecular Weight	254.45 g/mol
Synonyms	4-Methyl-5-chloro-2-iodopyrimidine; 2-Iodo-5-chloro-4-methylpyrimidine; 5-Chloro-2-iodo-4-methyl-pyrimidine; 1260810-52-3; 4-Methyl-2-iodo-5-chloropyrimidine; 5-Chloro-4-methyl-2-iodopyrimidine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Iodo-4-Methylpyrimidine is produced under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.