Description

Methyl-(5-Methyl-Pyrimidin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering significant value in creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for its role in developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its pyrimidine core structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for various industrial applications.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	Methyl-(5-Methyl-Pyrimidin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1260807-65-5
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	tert-Butyl N-methyl-N-(5-methylpyrimidin-2-yl)carbamate; N-Methyl-N-(5-methyl-2-pyrimidinyl)carbamic Acid 1,1-Dimethylethyl Ester; 2-[(tert-Butoxycarbonyl)(methyl)amino]-5-methylpyrimidine; BOC-Protected Methyl-(5-Methyl-Pyrimidin-2-Yl)amine; Methyl(5-methylpyrimidin-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Methyl-(5-Methyl-Pyrimidin-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ICH Q7 guidelines, and relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.