Description

4-(Azetidin-1-Ylmethyl)-3-Fluorophenol is a fluorinated phenolic compound featuring an azetidine moiety, making it a valuable and versatile building block in advanced organic synthesis. Its molecular architecture is specifically designed to serve as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals. This compound is primarily targeted at research and development teams, medicinal chemists, and process chemists within the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis due to its unique azetidine and fluorophenol functional groups.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: The phenolic and heterocyclic nitrogen can be utilized to create novel ligands for catalysis or metal-organic frameworks (MOFs).
• Material Science Precursor: Potential use in the synthesis of advanced polymers and functional materials with specific optical or electronic properties.

Basic Information

Product Name	4-(Azetidin-1-Ylmethyl)-3-Fluorophenol
CAS No.	1260807-51-9
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	3-Fluoro-4-(azetidin-1-ylmethyl)phenol; 1-[(5-Fluoro-2-hydroxyphenyl)methyl]azetidine; 4-(Azetidin-1-ylmethyl)-3-fluorophenol; Azetidine, 1-[(5-fluoro-2-hydroxyphenyl)methyl]-; Phenol, 3-fluoro-4-(azetidin-1-ylmethyl)-
EINECS	Contact for details

Quality Control

Our 4-(Azetidin-1-Ylmethyl)-3-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.