Description

6-Bromo-2-(4-Bromo-2-Fluorophenyl)Quinazoline is a high-purity, multi-halogenated quinazoline derivative, a critical advanced intermediate in modern pharmaceutical and agrochemical research. Its value lies in its unique molecular scaffold, which serves as a versatile building block for constructing complex molecules with targeted biological activity. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly in the synthesis of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and cellular pathways.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to its reactive bromine substituents.
• Material Science Research: Investigated as a potential component in the synthesis of organic electronic materials.

Basic Information

Product Name	6-Bromo-2-(4-Bromo-2-Fluorophenyl)Quinazoline
CAS No.	1260784-16-4
Molecular Formula	C14H7Br2FN2
Molecular Weight	382.02 g/mol
Synonyms	2-(4-Bromo-2-fluorophenyl)-6-bromoquinazoline; 6-Bromo-2-(4-bromo-2-fluorophenyl)quinazoline; Quinazoline, 6-bromo-2-(4-bromo-2-fluorophenyl)-; 1260784-16-4; 6-Bromo-2-(4-bromo-2-fluoro-phenyl)quinazoline; 2-(4-Bromo-2-fluoro-phenyl)-6-bromo-quinazoline
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2-(4-Bromo-2-Fluorophenyl)Quinazoline is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.