Description

5-(Aminomethyl)-4-(Trifluoromethyl)Pyrimidin-2-Amine is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aminomethyl and a trifluoromethyl group, makes it a valuable intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides where the trifluoromethyl group improves metabolic stability and lipophilicity.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes, enzyme inhibitors, and labeled compounds for biochemical research.
• Material Science: Intermediate for creating specialty polymers, liquid crystals, and electronic materials that require specific fluorine-containing motifs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up development.

Basic Information

Product Name	5-(Aminomethyl)-4-(Trifluoromethyl)Pyrimidin-2-Amine
CAS No.	1260783-73-0
Molecular Formula	C6H7F3N4
Molecular Weight	192.14 g/mol
Synonyms	4-(Trifluoromethyl)-5-(aminomethyl)-2-pyrimidinamine; 2-Pyrimidinamine, 5-(aminomethyl)-4-(trifluoromethyl)-; 5-(Aminomethyl)-4-trifluoromethylpyrimidin-2-ylamine; 4-Trifluoromethyl-5-aminomethyl-pyrimidin-2-ylamine; 5-(Aminomethyl)-4-(trifluoromethyl)-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-4-(Trifluoromethyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.