Description

2-Chloro-4-Fluoro-3-Methylbenzaldehyde is a versatile halogenated benzaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive aldehyde group and specific halogen substitution pattern, enabling precise molecular construction for high-value intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes.
• Fine Chemical Production: Intermediate for synthesizing dyes, pigments, and other specialty chemicals requiring specific halogenation patterns.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig amination for creating complex biaryl structures.
• Academic & R&D: Valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	2-Chloro-4-Fluoro-3-Methylbenzaldehyde
CAS No.	1260764-27-9
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	3-Methyl-2-chloro-4-fluorobenzaldehyde; 2-Chloro-4-fluoro-3-methyl-benzaldehyde; Benzaldehyde, 2-chloro-4-fluoro-3-methyl-; 4-Fluoro-2-chloro-3-methylbenzaldehyde; 2-Chloro-4-fluoro-m-tolualdehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-3-Methylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.