Description

1-(5-(Trifluoromethyl)Pyrimidin-2-Yl)Ethan-1-Amine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced chemical synthesis. This compound matters as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl and amine groups offer unique reactivity and properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this specific pharmacophore into their molecular targets.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects.

Basic Information

Product Name	1-(5-(Trifluoromethyl)Pyrimidin-2-Yl)Ethan-1-Amine
CAS No.	1260670-90-3
Molecular Formula	C7H8F3N3
Molecular Weight	191.16 g/mol
Synonyms	1-[5-(Trifluoromethyl)pyrimidin-2-yl]ethanamine; 1-(5-(Trifluoromethyl)-2-pyrimidinyl)ethylamine; 2-(1-Aminoethyl)-5-(trifluoromethyl)pyrimidine; Ethanamine, 1-[5-(trifluoromethyl)-2-pyrimidinyl]-; 1-(5-Trifluoromethyl-pyrimidin-2-yl)-ethylamine
EINECS	Contact for details

Quality Control

Our 1-(5-(Trifluoromethyl)Pyrimidin-2-Yl)Ethan-1-Amine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.