Description

1-(2,3-Difluorophenyl)Cyclopropanemethanamine is a high-value, functionalized cyclopropane derivative featuring a primary amine group and a difluorinated aromatic ring. This unique structure makes it a critical pharmaceutical intermediate and a versatile building block for advanced organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, where the difluorophenyl and cyclopropane motifs are common.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific electronic or structural properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study biological pathways and enzyme functions.

Basic Information

Product Name	1-(2,3-Difluorophenyl)Cyclopropanemethanamine
CAS No.	1260663-44-2
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	1-(2,3-Difluorophenyl)cyclopropanemethanamine; [1-(2,3-Difluorophenyl)cyclopropyl]methanamine; 1-(2,3-Difluorophenyl)cyclopropylmethylamine; Cyclopropanemethanamine, 1-(2,3-difluorophenyl)-; 2,3-Difluoro-α-(aminomethyl)cyclopropylbenzene; (1-(2,3-Difluorophenyl)cyclopropyl)methanamine
EINECS	Contact for details

Quality Control

Our 1-(2,3-Difluorophenyl)Cyclopropanemethanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.