Description

(5-Hydroxymethyl-Pyrimidin-2-Yl)-Methyl-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is essential for research institutions, CROs, and manufacturers engaged in developing novel small-molecule drugs, agrochemicals, and other fine chemical products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrimidine core structure.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker molecule in the design of chemical probes and inhibitors for target identification and validation.
• Academic & Industrial R&D: Employed in methodological studies and the exploration of new synthetic routes for complex heterocyclic compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	(5-Hydroxymethyl-Pyrimidin-2-Yl)-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1260642-19-0
Molecular Formula	C12H19N3O3
Molecular Weight	253.30 g/mol
Synonyms	tert-Butyl N-[(5-hydroxymethylpyrimidin-2-yl)methyl]carbamate; N-[(5-Hydroxymethyl-2-pyrimidinyl)methyl]carbamic Acid 1,1-Dimethylethyl Ester; BOC-Protected 5-Hydroxymethyl-2-pyrimidinemethylamine; (5-Hydroxymethyl-2-pyrimidinyl)methylcarbamic Acid tert-Butyl Ester; 2-(((tert-Butoxycarbonyl)amino)methyl)pyrimidine-5-methanol; BOC-Aminomethyl-(5-hydroxymethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our (5-Hydroxymethyl-Pyrimidin-2-Yl)-Methyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.