Description

Fmoc-Hph(2-Me)-Oh CAS NO 1260612-11-0 is a protected amino acid derivative, specifically an Fmoc-protected homophenylalanine analog with a methyl substituent. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity, specialized amino acids for drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key monomer for the automated synthesis of therapeutic and research peptides.
• Pharmaceutical Intermediates: Used in the development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Serves as a modified amino acid linker for creating peptide-protein or peptide-small molecule conjugates.
• Chemical Biology Research: Employed in the study of protein-protein interactions and enzyme mechanisms by incorporating non-natural amino acids.
• Peptidomimetic Design: Facilitates the creation of peptide analogs with enhanced stability, bioavailability, or receptor affinity.
• Combinatorial Library Synthesis: A valuable component for generating diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	Fmoc-Hph(2-Me)-Oh
CAS No.	1260612-11-0
Molecular Formula	C26H25NO4
Molecular Weight	415.48 g/mol
Synonyms	Fmoc-2-methyl-homophenylalanine-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-homophenylalanine; Fmoc-2-Me-Hph-OH; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-(2-methylphenyl)butanoic acid; Fmoc-L-2-methylhomoPhe-OH; Fmoc-(2-methyl)homophenylalanine; Nα-Fmoc-2-methyl-L-homophenylalanine; Protected 2-methylhomophenylalanine
EINECS	Contact for details

Quality Control

Our Fmoc-Hph(2-Me)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates, with specifications available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.