Description

(S)-(9H-Fluoren-9-Yl)Methoxy]Carbonyl Phg(4-Methoxy)-Oh (Ee 95%) CAS NO 1260596-73-3 is a high-purity, non-natural amino acid derivative featuring a 4-methoxy-substituted phenylglycine (Phg) backbone protected by the 9-fluorenylmethoxycarbonyl (Fmoc) group. This compound is critical for the synthesis of complex peptides with specific stereochemical and functional properties, enabling advanced research and development. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and academic researchers working on novel therapeutic peptides, peptidomimetics, and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected building block for the controlled, sequential assembly of custom peptides.
• Pharmaceutical Research: For the development of peptide-based drug candidates, hormone analogs, and diagnostic agents requiring high enantiomeric purity.
• Peptidomimetic Design: Incorporation into non-peptide scaffolds to enhance metabolic stability and bioavailability of lead compounds.
• Bioconjugation: Used to introduce the 4-methoxyphenylglycine moiety into proteins, antibodies, or other biomolecules for labeling or functionalization.
• Chemical Biology Probes: Synthesis of labeled or tagged peptides for studying protein-protein interactions and cellular pathways.
• Academic & Contract Research: A fundamental reagent for universities and CROs exploring new peptide sequences and structures.

Basic Information

Product Name	(S)-(9H-Fluoren-9-Yl)Methoxy]Carbonyl Phg(4-Methoxy)-Oh (Ee 95%)
CAS No.	1260596-73-3
Molecular Formula	C25H23NO5
Molecular Weight	417.46 g/mol
Synonyms	Fmoc-4-Methoxy-D-phenylglycine; Fmoc-(4-MeO)-D-Phg-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methoxy-D-phenylglycine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-methoxyphenyl)acetic acid; Fmoc-D-4-methoxyphenylglycine; N-Fmoc-4-methoxy-D-phenylglycine; Fmoc-D-Phe(4-OMe)-OH; Fmoc-4-MeO-Phg-OH
EINECS	Contact for details

Quality Control

Every batch of this amino acid derivative is produced under strict quality management systems. We guarantee the specified 95% enantiomeric excess (Ee) and high chemical purity through comprehensive analytical techniques including HPLC, NMR, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and chiral purity to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Ee)	≥ 95.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.