Description

n-Fmoc-3-Methyl-L-Homophenylalanine CAS NO 1260594-53-3 is a protected, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for the development of novel peptide-based pharmaceuticals and research tools, offering precise structural control. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity intermediates for solid-phase peptide synthesis (SPPS).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled assembly of complex peptides.
• Pharmaceutical Research: Used in the discovery and development of novel therapeutic peptides, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Incorporates a modified phenylalanine side chain to enhance metabolic stability, bioavailability, and receptor binding affinity in peptide mimics.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged peptides used in biochemical assays and diagnostic research.
• Combinatorial Chemistry Libraries: Employed to generate diverse arrays of peptide compounds for high-throughput screening against biological targets.

Basic Information

Product Name	n-Fmoc-3-Methyl-L-Homophenylalanine
CAS No.	1260594-53-3
Molecular Formula	C26H25NO4
Molecular Weight	415.48 g/mol
Synonyms	Fmoc-3-Me-Hph-OH; Fmoc-3-methyl-L-homophenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methyl-L-homophenylalanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-4-(3-methylphenyl)butanoic acid; Fmoc-3-methylhomoPhe-OH; 3-Methyl-L-homophenylalanine, N-Fmoc derivative; Fmoc-3-methyl-DL-homophenylalanine (racemic mixture)
EINECS	Contact for details

Quality Control

Our n-Fmoc-3-Methyl-L-Homophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.