Description

Benzenebutanoic Acid, 4-Ethyl-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is a specialized, high-purity chemical building block designed for advanced synthetic applications. Its core value lies in its role as a protected amino acid derivative, enabling precise and efficient peptide synthesis for research and development. This compound is essential for pharmaceutical chemists, biotech researchers, and fine chemical manufacturers engaged in the development of novel therapeutic peptides and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential addition of amino acids in automated peptide synthesis.
• Pharmaceutical Research & Development: Used in the discovery and development of new peptide-based drugs, including hormones, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation and Labeling: Serves as a precursor for creating peptide tags or probes used in biochemical assays and diagnostic tools.
• Fine Chemical Synthesis: Employed as a chiral building block for the synthesis of complex, non-peptidic molecules requiring specific stereochemistry.
• Academic and Institutional Research: A critical reagent for universities and research institutes studying protein structure, function, and peptide chemistry.
• Custom Peptide Manufacturing: Used by CROs and CDMOs to produce custom peptides for clients in the life sciences sector.

Basic Information

Product Name	Benzenebutanoic Acid, 4-Ethyl-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)-
CAS No.	1260593-21-2
Molecular Formula	C27H27NO4
Molecular Weight	429.51 g/mol
Synonyms	Fmoc-4-Ethyl-DL-homophenylalanine; Fmoc-DL-4-Ethyl-homoPhe-OH; (αS)-4-Ethyl-α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]benzenebutanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-ethyl-DL-homophenylalanine; Fmoc-4-Ethyl-hPhe-OH; Nα-Fmoc-4-ethyl-DL-homophenylalanine; Protected 4-ethyl-homophenylalanine; Fmoc-4-Et-hPhe-OH
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic workflows. Every lot is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to confirm identity, chiral purity, and chemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	Specified enantiomeric excess (ee) available
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.