Description

4-Fluoro-2-Methyl-1H-Indole is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on novel active ingredients, where its unique substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and receptor modulator programs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the bioactivity of the indole scaffold.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for studying biological systems.
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	4-Fluoro-2-Methyl-1H-Indole
CAS No.	1260383-51-4
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	4-Fluoro-2-methylindole; 2-Methyl-4-fluoro-1H-indole; 1H-Indole, 4-fluoro-2-methyl-; 4-Fluoro-2-methyl-1H-indole; 4-Fluoro-2-methylindole; 2-Methyl-4-fluoroindole; 4-Fluoro-2-methyl-1H-indole (CAS 1260383-51-4)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methyl-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.