Description

(tert-Butoxy)Carbonyl His(Dnp)-Oh·Ipa is a specialized, protected amino acid derivative used in advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity, custom building blocks for complex biomolecule construction. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel peptide-based therapeutics and research reagents.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key, side-chain protected histidine derivative for the controlled assembly of peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) for peptide drugs.
• Bioconjugation: Acts as a precursor for creating labeled peptides or peptide-protein conjugates for diagnostic and research applications.
• Chemical Biology Research: Employed in studying protein-protein interactions, enzyme mechanisms, and signal transduction pathways.
• Custom Peptide Service: A vital raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	(tert-Butoxy)Carbonyl His(Dnp)-Oh·Ipa
CAS No.	1260247-63-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Boc-His(Dnp)-OH·IPA; N-α-(tert-Butoxycarbonyl)-N-π-(2,4-dinitrophenyl)-L-histidine isopropylammonium salt; Boc-L-Histidine(Dnp)-OH IPA salt; Boc-His(Dnp)-OH isopropylamine salt; (tert-Butoxycarbonyl)-L-histidine(Dnp) isopropylammonium salt; Protected Histidine derivative; Boc-His(Dnp)-OH·iPrNH2; Fmoc-His(Dnp)-OH precursor
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl His(Dnp)-Oh·Ipa is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.