Description

Ethyl 2-Chloro-4-Methoxypyrimidine-5-Carboxylate is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive chloro and ester functional groups, enabling precise molecular construction. It is primarily sought after by research institutions and pharmaceutical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the pyrimidine core's bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific pyrimidine scaffolds.

Basic Information

Product Name	Ethyl 2-Chloro-4-Methoxypyrimidine-5-Carboxylate
CAS No.	1260178-65-1
Molecular Formula	C8H9ClN2O3
Molecular Weight	216.62 g/mol
Synonyms	2-Chloro-4-methoxypyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-chloro-4-methoxy-5-pyrimidinecarboxylate; 5-Carbethoxy-2-chloro-4-methoxypyrimidine; 2-Chloro-4-methoxy-5-pyrimidinecarboxylic acid ethyl ester; 1260178-65-1; Ethyl 2-chloro-4-methoxy-5-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-4-Methoxypyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.