Description

n-(3-(5-Chloro-2-Cyclopropoxyphenyl)-1H-Pyrazol-4-Yl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors.
• Preclinical Drug Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis for client drug discovery projects.
• Academic Research: Used in university and institutional labs for chemical biology and new therapeutic target exploration.

Basic Information

Product Name	n-(3-(5-Chloro-2-Cyclopropoxyphenyl)-1H-Pyrazol-4-Yl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide
CAS No.	1260164-11-1
Molecular Formula	C21H16ClN7O2
Molecular Weight	433.85 g/mol
Synonyms	5-Chloro-2-cyclopropoxy-N-[3-(5-chloro-2-cyclopropoxyphenyl)-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; 1260164-11-1; UNII-9H6W8S9Q0H; 9H6W8S9Q0H; Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(5-chloro-2-cyclopropoxyphenyl)-1H-pyrazol-4-yl]-5-chloro-2-cyclopropoxy-; CHEMBL3186609; BDBM50389357; AKOS009158932
EINECS	Contact for details

Quality Control

Our production of n-(3-(5-Chloro-2-Cyclopropoxyphenyl)-1H-Pyrazol-4-Yl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which are aligned with ICH guidelines for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.