Description

Amikacin (Hydrate) CAS NO 1257517-67-1 is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. It is valued for its broad-spectrum bactericidal activity, particularly against Gram-negative bacteria, including many strains resistant to other aminoglycosides. This compound is essential for pharmaceutical manufacturers and research institutions developing injectable antibiotic formulations and studying mechanisms of antimicrobial resistance.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of injectable antibiotic solutions for the treatment of serious systemic infections.
• Research & Development: Used in microbiological and pharmacological studies to investigate antibiotic efficacy, resistance patterns, and synergistic drug combinations.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or microbiological assay calibration.
• Veterinary Medicine: Employed in the development of treatments for bacterial infections in animals.
• Cell Culture Media Supplement: Used in selective media in research settings to prevent bacterial contamination.

Basic Information

Product Name	Amikacin (Hydrate)
CAS No.	1257517-67-1
Molecular Formula	C22H43N5O13 • xH2O
Molecular Weight	Anhydrous: 585.60 g/mol
Synonyms	Amikacin Hydrate; Amikacin Monohydrate; Amikacin Sesquihydrate; BB-K8; Amikacine; Amikacina; Amikacinum; (+)-Amikacin; 4-Amino-1-N-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-S-(3-amino-3-deoxy-α-D-glucopyranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-1,2,3,4-tetradeoxy-D-erythro-hex-2-enopyranuronamide Hydrate
EINECS	Contact for details

Quality Control

Our Amikacin (Hydrate) is manufactured under strict quality systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, purity, and identification. Specifications can be aligned with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	Contact for details
pH (Solution)	Contact for details
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Contact for details
Microbial Limits	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.