Description

n-(5-(3-Chlorophenyl)-2,7-Dioxo-1,2,4,7-Tetrahydropyrazolo[1,5-A]Pyrimidin-3-Yl)Acetamide is a high-purity, heterocyclic organic compound with the CAS number 1257440-43-9, serving as a critical pharmaceutical intermediate and research chemical. Its complex pyrazolopyrimidine core structure makes it a valuable building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• Kinase Inhibitor Development: The pyrazolopyrimidine moiety is a privileged structure in the design of protein kinase inhibitors for oncology and inflammatory diseases.
• Biochemical Tool Compound: Serves as a reference standard or probe molecule in biochemical and pharmacological assays.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology and heterocyclic chemistry studies.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial chemical entities for client-specific projects.

Basic Information

Product Name	n-(5-(3-Chlorophenyl)-2,7-Dioxo-1,2,4,7-Tetrahydropyrazolo[1,5-A]Pyrimidin-3-Yl)Acetamide
CAS No.	1257440-43-9
Molecular Formula	C15H11ClN4O3
Molecular Weight	330.73 g/mol
Synonyms	Acetamide, N-[5-(3-chlorophenyl)-2,7-dioxo-1,2,4,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl]-; 3-Acetamido-5-(3-chlorophenyl)-1,4-dihydropyrazolo[1,5-a]pyrimidine-2,7-dione; 1257440-43-9; N-(5-(3-Chlorophenyl)-2,7-dioxo-1,2,4,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)acetamide; Pyrazolo[1,5-a]pyrimidine-3-acetamide derivative
EINECS	Contact for details

Quality Control

Our n-(5-(3-Chlorophenyl)-2,7-Dioxo-1,2,4,7-Tetrahydropyrazolo[1,5-A]Pyrimidin-3-Yl)Acetamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.