Description

4-(1,1-Dimethylethyl)-n-[6-(Ethenyloxy)-5-(2-Methoxyphenoxy)[2,2''-Bipyrimidin]-4-Yl]-Benzenesulfonamide CAS NO 1257099-44-7 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially those targeting specific enzymatic pathways where such sulfonamide-bipyrimidine hybrids show promise.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of potential drug molecules.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of selective kinase inhibitors, a major class of targeted cancer therapies.
• Biochemical Tool Compound: Employed in vitro as a probe to study specific biological pathways and protein-ligand interactions.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	4-(1,1-Dimethylethyl)-n-[6-(Ethenyloxy)-5-(2-Methoxyphenoxy)[2,2''-Bipyrimidin]-4-Yl]-Benzenesulfonamide
CAS No.	1257099-44-7
Molecular Formula	C29H30N6O5S
Molecular Weight	574.65 g/mol
Synonyms	4-tert-Butyl-N-[6-(ethenyloxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; 4-(tert-Butyl)-N-[6-(vinyloxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide; Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-; Bipyrimidine sulfonamide derivative; CAS 1257099-44-7
EINECS	Contact for details

Quality Control

Our 4-(1,1-Dimethylethyl)-n-[6-(Ethenyloxy)-5-(2-Methoxyphenoxy)[2,2''-Bipyrimidin]-4-Yl]-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided and available upon request, supporting compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.