Description

[2-(4-Methylpiperazin-1-Yl)Pyrimidin-5-Yl]Boronic Acid is a high-value boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries who are developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for creating carbon-carbon bonds in complex molecule assembly.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, particularly in constructing heterocyclic scaffolds.
• Agrochemical Synthesis: Employed as an intermediate in the development of novel pesticides and herbicides.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	[2-(4-Methylpiperazin-1-Yl)Pyrimidin-5-Yl]Boronic Acid
CAS No.	1256355-29-9
Molecular Formula	C9H15BN4O2
Molecular Weight	222.06 g/mol
Synonyms	(2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)boronic acid; 2-(4-Methyl-1-piperazinyl)-5-pyrimidineboronic acid; 5-Borono-2-(4-methylpiperazin-1-yl)pyrimidine; [2-(4-Methyl-1-piperazinyl)-5-pyrimidinyl]boronic acid; Boronic acid, B-[2-(4-methyl-1-piperazinyl)-5-pyrimidinyl]-; 2-(4-Methylpiperazin-1-yl)pyrimidine-5-boronic acid; 2-(4-Methylpiperazin-1-yl)-5-pyrimidineboronic acid; CAS 1256355-29-9
EINECS	Contact for details

Quality Control

Our [2-(4-Methylpiperazin-1-Yl)Pyrimidin-5-Yl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.