Description

2,5-Difluoro-4-(1H-Tetrazol-1-Yl)Phenol is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining phenol, fluorine, and tetrazole functionalities. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those requiring a bioisostere for carboxylic acids.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Intermediate in the research and production of novel herbicides, fungicides, or insecticides.
• Ligand Synthesis: Preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for creating polymers with specific electronic or adhesive properties.
• Chemical Biology Probes: Synthesis of molecular tools for studying enzyme function or cellular processes.

Basic Information

Product Name	2,5-Difluoro-4-(1H-Tetrazol-1-Yl)Phenol
CAS No.	1255574-38-9
Molecular Formula	C7H4F2N4O
Molecular Weight	198.13 g/mol
Synonyms	4-(1H-Tetrazol-1-yl)-2,5-difluorophenol; 2,5-Difluoro-4-(1H-tetrazol-1-yl)phenol; 2,5-Difluoro-4-(tetrazol-1-yl)phenol; 1-(4-Hydroxy-2,5-difluorophenyl)-1H-tetrazole; Phenol, 2,5-difluoro-4-(1H-tetrazol-1-yl)-; 1255574-38-9
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-(1H-Tetrazol-1-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.