Description

1-(3-Fluoro-5-Methylphenyl)Propan-1-Amine is a fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine and methyl substituents on the phenyl ring can dramatically influence biological activity and metabolic stability. Pharmaceutical researchers and fine chemical manufacturers need this high-purity intermediate to create novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	1-(3-Fluoro-5-Methylphenyl)Propan-1-Amine
CAS No.	1255306-18-3
Molecular Formula	C10H14FN
Molecular Weight	167.22 g/mol
Synonyms	1-(3-Fluoro-5-methylphenyl)propan-1-amine; 3-Fluoro-5-methylbenzenepropanamine; 1-(3-Fluoro-5-methylphenyl)-1-propanamine; 3-Fluoro-5-methyl-β-methylphenethylamine; 3-Fluoro-5-methylphenylpropylamine; 1-Amino-1-(3-fluoro-5-methylphenyl)propane; Benzenepropanamine, 3-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-5-Methylphenyl)Propan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can supply material compliant with cGMP standards for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.