Description

4-Bromopyrimidine Hydrochloride is a high-purity organic salt derivative of pyrimidine, serving as a critical building block in advanced chemical synthesis. This compound is valued for its reactivity, particularly in cross-coupling reactions and as a precursor for more complex heterocyclic systems. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require functionalized pyrimidine cores.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Cross-Coupling Reactions: Acts as a versatile electrophile in Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Nucleoside & Nucleotide Chemistry: Serves as a halogenated base analog in the synthesis of modified nucleosides for biochemical research.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	4-Bromopyrimidine Hydrochloride
CAS No.	1255099-57-0
Molecular Formula	C4H4BrClN2
Molecular Weight	195.45 g/mol
Synonyms	4-Bromopyrimidine HCl; 4-Bromopyrimidine Hydrochloride Salt; Pyrimidine, 4-bromo-, hydrochloride (1:1); 4-Bromo-1,3-diazine hydrochloride; 4-Bromopyrimidinium chloride
EINECS	Contact for details

Quality Control

Our 4-Bromopyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.