Description

2,4-Dibromo-3-Fluoroaniline is a halogenated aniline derivative serving as a versatile and critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and fluorine substituents for bioactivity or material properties modulation.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the dibromo-fluoro substitution pattern enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex halogenated azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination, Suzuki, and other palladium-catalyzed cross-coupling reactions to create biaryl and aniline derivatives.
• Research & Development: Employed in academic and industrial labs for methodological studies in halogenation chemistry and the exploration of new heterocyclic systems.

Basic Information

Product Name	2,4-Dibromo-3-Fluoroaniline
CAS No.	1253889-53-0
Molecular Formula	C6H4Br2FN
Molecular Weight	268.91 g/mol
Synonyms	3-Fluoro-2,4-dibromoaniline; 2,4-Dibromo-3-fluoro-benzenamine; Benzenamine, 2,4-dibromo-3-fluoro-; 2,4-Dibromo-3-fluorophenylamine; Aniline, 2,4-dibromo-3-fluoro-; 3-Fluoro-2,4-dibromobenzenamine
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-3-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.