Description

Ethyl 8-Benzyl-5-Hydroxy-2-(Methylthio)-7-Oxo-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1253791-11-5. This compound is a critical building block in modern medicinal chemistry, valued for its complex heterocyclic structure which serves as a key scaffold in drug discovery and development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within oncology and antiviral research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted small-molecule drugs.
• Drug Discovery & Development: Used as a core scaffold for structure-activity relationship (SAR) studies in medicinal chemistry programs.
• Oncology Research: Investigated as a building block for potential kinase inhibitors and other anticancer agents.
• Antiviral Agent Synthesis: Employed in the research and development of novel antiviral compounds.
• Biochemical Research: Utilized as a standard or reagent in biochemical assays and proteomics studies.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for cGMP-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Ethyl 8-Benzyl-5-Hydroxy-2-(Methylthio)-7-Oxo-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	1253791-11-5
Molecular Formula	C19H17N3O4S
Molecular Weight	383.42 g/mol
Synonyms	8-Benzyl-5-hydroxy-2-(methylthio)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; Ethyl 8-benzyl-5-hydroxy-2-methylsulfanyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate; 1253791-11-5; Pyrido[2,3-d]pyrimidine-6-carboxylate derivative; SCHEMBL23583027
EINECS	Contact for details

Quality Control

Our production of Ethyl 8-Benzyl-5-Hydroxy-2-(Methylthio)-7-Oxo-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and cGMP-grade standards where applicable. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.