Description

7-Phenyl-1-(Prop-2-Ynyl)-1H-Pyrimido[4,5-D][1,3]Oxazine-2,4-Dione is a high-purity, advanced pharmaceutical intermediate with the CAS number 1253790-88-3. This heterocyclic compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in novel drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of target drug molecules, particularly in oncology and antiviral research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds due to its reactive functional groups.
• Research & Development (R&D): Essential for academic and industrial laboratories exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) supporting outsourced drug development projects.

Basic Information

Product Name	7-Phenyl-1-(Prop-2-Ynyl)-1H-Pyrimido[4,5-D][1,3]Oxazine-2,4-Dione
CAS No.	1253790-88-3
Molecular Formula	C₁₇H₁₁N₃O₃
Molecular Weight	305.29 g/mol
Synonyms	1H-Pyrimido[4,5-d][1,3]oxazine-2,4-dione, 7-phenyl-1-(2-propynyl)-; 7-Phenyl-1-(prop-2-yn-1-yl)-1H-pyrimido[4,5-d][1,3]oxazine-2,4(3H,7H)-dione; 1253790-88-3; 7-Phenyl-1-prop-2-ynyl-3,7-dihydro-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione
EINECS	Contact for details

Quality Control

Our 7-Phenyl-1-(Prop-2-Ynyl)-1H-Pyrimido[4,5-D][1,3]Oxazine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.