Description

Ethyl 5-Hydroxy-8-Isopropyl-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly those targeting kinase inhibition and other critical biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel small-molecule drug candidates for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies and lead optimization programs.
• Kinase Inhibitor Development: Its pyridopyrimidine core makes it a valuable intermediate for developing potent and selective kinase inhibitors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Ethyl 5-Hydroxy-8-Isopropyl-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	1253790-73-6
Molecular Formula	C21H21N3O4
Molecular Weight	379.41 g/mol
Synonyms	Ethyl 5-hydroxy-8-(propan-2-yl)-7-oxo-2-phenyl-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate; 7,8-Dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, 5-hydroxy-8-(1-methylethyl)-7-oxo-2-phenyl-, ethyl ester; 5-Hydroxy-8-isopropyl-7-oxo-2-phenyl-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; Ethyl 5-hydroxy-8-isopropyl-7-oxo-2-phenyl-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate; CAS 1253790-73-6
EINECS	Contact for details

Quality Control

Our Ethyl 5-Hydroxy-8-Isopropyl-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.