Description

4-Benzyloxy-2-(Trifluoromethyl)Benzayl Alcohol is a high-purity, advanced pharmaceutical intermediate characterized by its benzyl-protected alcohol and trifluoromethyl-substituted aromatic ring. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where the trifluoromethyl group is prized for enhancing metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for developing advanced pesticides and herbicides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal Materials: Used in the development of specialty organic compounds for electronic displays and optical devices.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED fabrication.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new chemical entities.
• Fine Chemical Production: Integral to custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Benzyloxy-2-(Trifluoromethyl)Benzayl Alcohol
CAS No.	1253188-22-5
Molecular Formula	C15H13F3O2
Molecular Weight	282.26 g/mol
Synonyms	[4-(Benzyloxy)-2-(trifluoromethyl)phenyl]methanol; 2-(Trifluoromethyl)-4-(phenylmethoxy)benzenemethanol; 4-Benzyloxy-2-trifluoromethylbenzyl Alcohol; 4-(Benzyloxy)-2-(trifluoromethyl)benzyl Alcohol; α-(4-Benzyloxy-2-trifluoromethylphenyl)methanol; (4-Benzyloxy-2-trifluoromethylphenyl)methanol; Benzenemethanol, [4-(phenylmethoxy)-2-(trifluoromethyl)-]; 1253188-22-5
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2-(Trifluoromethyl)Benzayl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.