Description

2-Cyclopropyl-6-Fluoroquinazolin-4(3H)-One is a high-value, fluorinated quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, particularly in the creation of novel small-molecule therapeutics. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of potential drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create complex, fluorinated heterocyclic compounds.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for proprietary research projects.

Basic Information

Product Name	2-Cyclopropyl-6-Fluoroquinazolin-4(3H)-One
CAS No.	1252134-65-8
Molecular Formula	C11H9FN2O
Molecular Weight	204.20 g/mol
Synonyms	6-Fluoro-2-cyclopropyl-3,4-dihydroquinazolin-4-one; 2-Cyclopropyl-6-fluoro-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-cyclopropyl-6-fluoro-; 6-Fluoro-2-cyclopropylquinazolin-4(3H)-one; 2-Cyclopropyl-6-fluoro-4-hydroxyquinazoline
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-6-Fluoroquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.