Description

3-Methylpyrrolidine-1-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile reagent for introducing the sulfonamide functional group, enabling the synthesis of complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating sulfonamide-based drugs with potential applications in various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonamide moiety can enhance biological activity and selectivity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling, modifying, or cross-linking biomolecules like proteins and peptides in research applications.
• Material Science Precursor: Employed in the synthesis of specialty polymers, dyes, and functional materials that require sulfonamide linkages for specific chemical or physical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Methylpyrrolidine-1-Sulfonyl Chloride
CAS No.	1251345-08-0
Molecular Formula	C5H10ClNO2S
Molecular Weight	183.66 g/mol
Synonyms	1-(Chlorosulfonyl)-3-methylpyrrolidine; 3-Methyl-1-pyrrolidinesulfonyl chloride; 3-Methylpyrrolidine sulfonyl chloride; N-(Chlorosulfonyl)-3-methylpyrrolidine; 3-Methylpyrrolidine-1-sulfonyl chloride; Pyrrolidine, 3-methyl-, 1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Methylpyrrolidine-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and our quality management system is designed to meet the rigorous requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.