Description

1-(4-Fluorobenzyl)-3-Methyl-1H-Pyrazol-5-Amine is a high-purity, fluorinated pyrazole derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated heterocyclic moiety into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole core.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or molecular probes used in biochemical and pharmacological studies.
• Material Science Research: Potential monomer or additive in the synthesis of specialized polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(4-Fluorobenzyl)-3-Methyl-1H-Pyrazol-5-Amine
CAS No.	1251280-29-1
Molecular Formula	C11H12FN3
Molecular Weight	205.23 g/mol
Synonyms	5-Amino-1-(4-fluorobenzyl)-3-methyl-1H-pyrazole; 3-Methyl-1-(4-fluorobenzyl)-1H-pyrazol-5-amine; 1H-Pyrazol-5-amine, 1-[(4-fluorophenyl)methyl]-3-methyl-; 1-(4-Fluorobenzyl)-3-methylpyrazol-5-amine; 1-(4-Fluorobenzyl)-3-methyl-1H-pyrazol-5-ylamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed batch-specific results are available upon request. We adhere to a quality management system and can support development projects requiring GMP (Good Manufacturing Practice) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.