Description

3-Bromo-1H-Pyrazolo[3,4-D]Pyrimidine CAS NO 1251033-27-8 is a high-purity, heterocyclic organic compound featuring a brominated pyrazolopyrimidine scaffold. This versatile building block is crucial for advanced pharmaceutical research and development, particularly in the synthesis of kinase inhibitors and other targeted therapeutics. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a starting material for creating labeled probes or active pharmaceutical ingredients (APIs) for biological testing.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecules for agrochemical and material science applications.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP or research-grade conditions.

Basic Information

Product Name	3-Bromo-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1251033-27-8
Molecular Formula	C5H3BrN4
Molecular Weight	198.99 g/mol
Synonyms	3-Bromo-1H-pyrazolo[3,4-d]pyrimidine; 3-Bromo-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 3-bromo-; 3-Bromopyrazolo[3,4-d]pyrimidine; 3-Bromo-7-azaindazole; 3-Bromo-1H-1,2,3-triazolo[4,5-d]pyrimidine (obsolete); 1251033-27-8; 3-Bromo-7H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 3-Bromo-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.