Description

7,8-Dihydro-4H,6H-1,5,8A-Triaza-Azulene-5,7-Dicarboxylic Acid 5-tert-Butyl Ester(Wx140191) is a high-purity, advanced pharmaceutical intermediate characterized by its unique triaza-azulene heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing novel heterocyclic scaffolds due to its reactive ester and protected carboxylic acid functionalities.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and exploratory synthesis.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of target molecules, where consistent quality is paramount.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) supporting outsourced drug development pipelines.

Basic Information

Product Name	7,8-Dihydro-4H,6H-1,5,8A-Triaza-Azulene-5,7-Dicarboxylic Acid 5-tert-Butyl Ester(Wx140191)
CAS No.	1251017-61-4
Molecular Formula	C14H19N3O4
Molecular Weight	293.32 g/mol
Synonyms	5-tert-Butyl 7H-7,8-dihydro-4H,6H-1,5,8a-triazaazulene-5,7-dicarboxylate; 1,5,8a-Triazaazulene-5,7-dicarboxylic acid, 7,8-dihydro-4H,6H-, 5-(1,1-dimethylethyl) ester; WX-140191; Wx140191; tert-Butyl 7,8-dihydro-4H,6H-1,5,8a-triazaazulene-5-carboxylate-7-carboxylate; CAS 1251017-61-4
EINECS	Contact for details

Quality Control

Our 7,8-Dihydro-4H,6H-1,5,8A-Triaza-Azulene-5,7-Dicarboxylic Acid 5-tert-Butyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.