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2-Cyclopropyl-4-Fluoroaniline CAS NO 1250966-57-4


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CAS No.:1250966-57-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Cyclopropyl-4-Fluoroaniline is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the cyclopropyl and fluoro substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental persistence.
  • Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
  • Chemical Research & Development: Employed in academic and industrial labs for methodological studies in cross-coupling reactions, amide bond formation, and other C-N bond constructing processes.
  • Dye and Pigment Intermediate: Acts as a starting material for synthesizing novel fluorinated dyes and pigments with unique optical properties.

Basic Information

Product Name 2-Cyclopropyl-4-Fluoroaniline
CAS No. 1250966-57-4
Molecular Formula C9H10FN
Molecular Weight 151.18 g/mol
Synonyms 4-Fluoro-2-cyclopropylaniline; 2-Cyclopropyl-4-fluoro-benzenamine; 1-Cyclopropyl-2-fluoro-4-aminobenzene; Benzenamine, 2-cyclopropyl-4-fluoro-; 4-Fluoro-2-cyclopropylphenylamine; 2-Amino-5-fluorocyclopropylbenzene; 2-Cyclopropyl-4-fluoro-phenylamine
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Quality Control

Our 2-Cyclopropyl-4-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, prolonged exposure to air and light should be avoided.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Standard Grade)
Purity (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Related Substances (HPLC) Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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