Description

1-n-Benzyl-5-Fluorobenzene-1,2-Diamine is a high-purity fluorinated aromatic diamine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a benzyl-protected amine and a fluorine substituent, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to develop novel herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, such as polyimides and epoxy resins, for high-performance applications.
• Chemical Biology & Proteomics: Employed as a building block for fluorescent probes, affinity labels, and other molecular tools used in biochemical research.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a component in the synthesis of electron-transport or emissive layer materials for display technologies.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in palladium-catalyzed cross-coupling and reductive amination reactions.

Basic Information

Product Name	1-n-Benzyl-5-Fluorobenzene-1,2-Diamine
CAS No.	1250244-09-7
Molecular Formula	C₁₃H₁₃FN₂
Molecular Weight	216.26 g/mol
Synonyms	1-Benzyl-5-fluoro-1,2-benzenediamine; 5-Fluoro-1,2-phenylenediamine N-benzyl derivative; N1-Benzyl-5-fluoro-1,2-benzenediamine; 1,2-Benzenediamine, 5-fluoro-N1-(phenylmethyl)-; 5-Fluoro-N1-benzylbenzene-1,2-diamine; 1-Benzyl-5-fluoro-1,2-diaminobenzene; 1,2-Diamino-4-fluorobenzene N-benzyl derivative
EINECS	Contact for details

Quality Control

Our 1-n-Benzyl-5-Fluorobenzene-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued light or using amber glass containers for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.