Description

2-(Tetrahydro-2H-Pyran-4-Yl)Pyrimidin-4-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and industrial R&D departments within the pharmaceutical, agrochemical, and fine chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Material Science Precursor: Potential intermediate in the synthesis of specialty chemicals and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex heterocyclic fragments.

Basic Information

Product Name	2-(Tetrahydro-2H-Pyran-4-Yl)Pyrimidin-4-Ol
CAS No.	1250122-56-5
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	4-Pyrimidinol, 2-(tetrahydro-2H-pyran-4-yl)-; 2-(Oxan-4-yl)pyrimidin-4-ol; 2-(Tetrahydro-2H-pyran-4-yl)-4-pyrimidinol; 2-(Tetrahydro-2H-pyran-4-yl)pyrimidin-4(1H)-one (tautomer); THP-Pyrimidinol; 1250122-56-5; 2-(Tetrahydropyran-4-yl)pyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-2H-Pyran-4-Yl)Pyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.